2020

Sabbagh M.F., Nathans J. (2020) A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture. eLife 9:e51276 doi: 10.7554/eLife.51276.  [ link ] [ pdf ]
Putnam A, Cassani M, Smith J, Seydoux G. (2020) Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos. Nature Structural & Molecular Biology. doi: 10.1038/s41594-019-0367-y. PubMed PMID:31896770. [ link ]

2019

Park, E, Scott, PM, Clutario, KM, Cassidy, KB, Zhan, K, Gerber and Holland, AJ. (2019) WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication. Journal of Cell Biology 219 (1): e201904203. [ link ] [ pdf ]
Mercey, O*, Levine, M.S*, LoMastro, G, Rostaing, P, Brotslaw, E, Gomez, V, Kumar, A, Spassky, N, Mitchell, BJ, Meunier, A* and Holland, AJ.* (2019) Massive centriole production can occur in the absence of deuterosomes in multiciliated cells. Nature Cell Biology 21: 1544-52. (2019). *equal contribution [ link ] [ pdf ]
Alexandre Paix, Dominique Rasoloson, Andrew Folkmann, and Geraldine Seydoux (2019). Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double-Stranded DNA Donors. Current Protocols in Molecular Biology e102, Volume 129. [ link ]
Heng J.S., Hackett S.F., Stein-O'Brien G.L., Winer B.L., Williams J., Goff L.A., Nathans J. (2019) Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America 116 (52) 26734-26744. [ link ] [ pdf ]
Lee, CY, Putnam, A, Lu T., Seydoux, G 2019. Recruitment of mRNAs to P granules by gelation with intrinsically-disordered proteins. http://biorxiv.org/cgi/content/short/732057v1. [ pdf ]
Ouyang, JPT, Folkmann, A, Bernard, L, Lee, CY, Seroussi, U, Charlesworth, AG et al. P Granules Protect RNA Interference Genes from Silencing by piRNAs. Dev. Cell. 2019; :. doi: 10.1016/j.devcel.2019.07.026. [ pdf ]
Cable, J, Brangwynne, C, Seydoux, G, Cowburn, D, Pappu, RV, Castañeda, CA et al. Phase separation in biology and disease-a symposium report. Ann. N. Y. Acad. Sci. 2019;1452 (1):3-11. doi: 10.1111/nyas.14126. [ pdf ]
Putnam, A, Cassani, M, Smith, J, Seydoux, G. A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos. Nat. Struct. Mol. Biol. 2019;26 (3):220-226. doi: 10.1038/s41594-019-0193-2. [ pdf ]
Folkmann, AW, Seydoux, G. Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms. Development. 2019;146 (6):. doi: 10.1242/dev.171116.  [ pdf ]
Lee, CY, Seydoux, G. Dynamics of mRNA entry into stress granules. Nat. Cell Biol. 2019;21 (2):116-117. doi: 10.1038/s41556-019-0278-5. [ pdf ]
Paix A, Rasoloson D, Folkman A, Seydoux G. (2019) Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double‐Stranded DNA Donors. Current Protocols in Molecular Biology Volume 129, e102. doi: 10.1002/cpmb.102 [ link ]
Rattner A., Williams J., Nathans J. (2019) Roles of HIFs and VEGF in angiogenesis in the retina and brain. The Journal of Clinical Investigation 129 (9):3807-3820. [ link ] [ pdf ]
Pike AM, Strong MA, Ouyang JPT, Greider CW. (2019) TIN2 functions with TPP1/POT1 to stimulate telomerase processivity. American Society for Microbiology ASM:doi: https://doi.org/10.1128/MCB.00593-18. [ link ] [ pdf ]
Peng X, Williams J, Smallwood PM, Nathans J. (2019) Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis. PLoS ONE 14(7):e0219384. [ link ] [ pdf ]
Cho, C., Wang, Y., Smallwood, P.M., Williams, J., Nathans, J. (2019) Molecular determinants in Frizzled, Reck, and Wnt7a for ligand-specific signaling in neurovascular development.  eLife 8: e47300. [ pdf ]
D'Orazio KN, Wu CC, Sinha NK, Loll-Krippleber R, Brown GW, Green R. (2019) The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay. eLife 2019;8:e49117 doi: 10.7554/eLife.49117 [ link ] [ pdf ]
Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. (2019) Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes and Development 33: 871-885. [ link ] [ pdf ]
Moyer TC, Holland AJ. (2019) PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole to the microtubule wall. eLife 8: e46054.  [ link ] [ pdf ]
Cho C., Wang Y., Smallwood P.M., Williams J., Nathans J. (2019) Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers. eLife 2019;8:e45542 doi: 10.7554/eLife.45542. [ link ] [ pdf ]
LoMastro GM, Holland AJ. (2019) The emerging link between centrosome aberrations and metastasis. Developmental Cell 49(3): 325-31. (2019). [ link ] [ pdf ]
DeFelice MM, Clark HR, Hughey JJ, Maayan I, Kudo T, Gutschow MV, Covert MW, Regot S. (2019) NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop. Science Signaling. 12(579). pii: eaau3568. doi: 10.1126/scisignal.aau3568.   [ link ] [ pdf ]
Wang, Y, Sabbagh, MF,  Gu, X, Rattner, A, Williams, J, and Nathans, J. (2019) Beta-catenin signaling regu lates barrier-specific gene expression in circumventricular organ and ocular vasculatures.  eLife 8: e43257. [ pdf ]
Heng, J.S., Rattner, A., Stein-O’Brien, G.L., Winer, B.L., Jones, B.W., Vernon, H.J., Goff, L.A., and Nathans, J . (2019)  Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. Proceedings of the National Academy of Sciences USA  116:9103-9114. [ pdf ]
Mohammad F, Green R, Buskirk AR. (2019)  A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution. Elife. 2019 Feb 6;8. pii: e42591.  [ link ]
Wu CC, Zinshteyn B, Wehner KA, Green R. (2019) High-Resolution Ribosome Profiling Defines Discrete Ribosome Elongation States and Translational Regulation during Cellular Stress. Mol Cell. 2019 Jan 11. pii: S1097-2765(18)31063-3. [ link ]
Zinshteyn B, Chan D, England W, Feng C, Green R, Spitale RC. (2019) Assaying RNA structure with LASER-Seq. Nucleic Acids Res. 2019 Jan 10;47(1):43-55.  [ link ]
Corden JL.  (2019)  An Arginine Nexus in the RNA Polymerase II CTD. Mol Cell. 2019 Jan 3;73(1):3-4.  [ link ]
Breslow DK, Holland AJ. (2019) Mechanism and regulation of centriole and cilium biogenesis. Annual Review of Biochemistry. 88: 691-724.  [ link ] [ pdf ]
Kreutzberger A, Ji M, Aaron J, Mihaljevic LjUrban S. (2019) Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion. Science 363(6426):497 [ link ] [ pdf ]

2018

Wang, Y., Cho, C., Williams, J., Smallwood, P.M., Zhang, C.,  Junge, H.J., and Nathans, J. (2018) Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance. Proceedings of the National Academy of Sciences USA 15: E11827-E11836. [ pdf ]
Peng, X., Emiliani, F., Smallwood, P.M., Rattner, A., Lei, H., Sabbagh, M.F., and Nathans, J.  (2018) Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions.  eLife 7: e40982. [ pdf ]
Sabbagh, M.F., Heng, J.S., Luo, C., Castanon, R.G., Nery, J.R., Rattner, A., Goff, L.A., Ecker, J.R., Nathans, J. (2018) Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. eLife 7: e36187 [ pdf ]
Wagner CL, Hanumanthu VS, Talbot CC Jr, Abraham RS, Hamm D, Gable DL, Kanakry CG, Applegate CD, Siliciano J, Jackson JB, Desiderio S, Alder JK, Luznik L, Armanios M. (2018) Short telomere syndromes cause a primary T cell immunodeficiency. J Clin Invest. 2018 Dec 3;128(12):5222-5234.  [ link ]
Luo J, Sun X, Cormack BP, Boeke JD. (2018) Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast. Nature. 2018 Aug;560(7718):392-396. [ link ]
Ward A, Kumari G, Sen R, Desiderio S. (2018) The RAG-2 Inhibitory Domain Gates Accessibility Of The V(D)J Recombinase To Chromatin. Mol Cell Biol. 2018 May 14. pii: MCB.00159-18.  [ link ]
Levine, M.S., Holland, A.J. (2018) The impact of mitotic errors on cell proliferation and tumorigenesis. Genes and Development 32(9-10): 620-38. [ link ] [ pdf ]
Jonathan K. Alder, Vidya Sagar Hanumanthu, Margaret A. Strong, Amy E. DeZern, Susan E. Stanley, Clifford M. Takemoto, Ludmilla Danilova, Carolyn D. Applegate, Stephen G. Bolton, David W. Mohr, Robert A. Brodsky, James F. Casella, Carol W. Greider, J. Brooks Jackson and Mary Armanios. (2018) Diagnostic utility of telomere length testing in a hospital-based setting. PNAS 115 (10): E2358-E2365 [ link ] [ pdf ]
Chen, H., Xue, J., Churikov, D., Hass, E.P., Lemon, L.D., Luciano, P., Bertuch, A.A., Zappulla, D.C., Geli, V., Wu, J., and Lei.M. (2018) Structural insights into yeast telomerase telomerase recruitment to telomeres. Cell 172:331–343  [ link ]
Hass, E.P. and Zappulla, D.C. (2017) A yeast two-hybrid system based on CRISPR-dCas9 for investigating RNA-protein interactions. bioRxiv doi: https://doi.org/10.1101/139600 [ link ]
Nigg, E.A., Holland, A.J. (2018) Once and only once: mechanisms of centriole duplication and their deregulation in disease. Nature Reviews Molecular Cell Biology 19(5): 297-312. [ link ] [ pdf ]
Lu W, Dordai D, Huso D, Desiderio S. (2018) Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis. Blood. 2018 Jan 18;131(3):323-327.  [ link ]
Chang, H., Smallwood, P.M., Williams, J., and Nathans, J. (2017) Intramembrane proteolysis of Astrotactins.  Journal of Biological Chemistry 292: 3506-3516. [ pdf ]
Goldberg, GW, McMillan EA, Varble A, Modell JW, et al. (2018) Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts. Nat Commun. 9(1):61. [ link ] [ pdf ]

2017

Kudo T, Jeknić S, Macklin DN, Akhter S, Hughey JJ, Regot S, Covert MW. (2018) Live-cell measurements of kinase activity in single cells using translocation reporters. Nature Protocols 13(1):155-169. doi: 10.1038/nprot.2017.128.   [ link ] [ pdf ]
Paix A, Folkmann A, Goldman DH, Kulaga H, Grzelak MJ, Rasoloson D, Paidemarry S, Green R, Reed RR, Seydoux G. (2017) Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks. Proc Natl Acad Sci U S A. (2017) Dec 12;114(50):E10745-E10754. [ link ]
Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Doré LC, Jin P, Regot S, Zhuang X, Canzar S, He C, Ming GL, Song H. (2017) Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation. Cell 171(4):877-889.e17.   [ link ] [ pdf ]
Xiao H, Wang F, Wisniewski J, Shaytan AK, Ghirlando R, Fitzgerald P, Huang Y, Wei D, Li S, Landsman D, Panchenko AR, Wu C. Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres. Genes Dev. Oct 26 Epub ahead of print, PMID 29074736 (2017). [ link ]
Mok CA, Au V, Thompson OA, Edgley ML, Gevirtzman L, Yochem J, Lowry J, Memar N, Wallenfang MR, Rasoloson D, Bowerman B, Schnabel R, Seydoux G, Moerman DG, Waterston RH. (2017) MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes. Genetics Oct;207(2):447-463.  [ link ]
Shaytan AK, Xiao H, Armeev GA, Wu C, Landsman D, Panchenko AR. (2017) Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning. Nucleic Acids Res. Sep 19; 45(16):9229-9243, PMID 28934480. [ link ] [ pdf ]
Merran J, Corden JL. (2017) Yeast RNA-Binding Protein Nab3 Regulates Genes Involved in Nitrogen Metabolism. Mol Cell Biol. 2017 Aug 28;37(18).    [ link ]
Wang, S., Pike, A. M., Lee, S. S., Strong, M.A., Connelly, C.J., Greider, C.W. (2017) BRD4 inhibitors block telomere elongation. Nucleic Acids Research. 45(14): 8403-8410.  [ link ] [ pdf ]
Claire de la Cova, Robert Townley, Sergi Regot, Iva Greenwald. (2017). A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification. Developmental Cell DOI: http://dx.doi.org/10.1016/j.devcel.2017.07.014     [ link ] [ pdf ]
Cho, C., Smallwood, P.M., Nathans, J. (2017) Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron 95 (5): 1056-1076 [ pdf ]
Modell JW, Jiang W, Marraffini LA. (2017) CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity. Nature 544(7648):101-104.   [ link ] [ pdf ]
Bettridge J, Na CH, Pandey A, Desiderio S. (2017) H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1904-1909. [ link ]
Levine, M.S., Bakker, B., Boeckx, B., Moyett, J., Lu, J., Vitre, B., Spierings, D.C., Lansdorp, P.M., Cleveland, D.W., Lambrechts, D., Foijer, F. and Holland, A.J. (2017) Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals. Developmental Cell 40(3): 313-22. (2017). [ link ] [ pdf ]

2016

Urban S. (2016) Cartography of intramembrane proteolysis. Cell 167(7):1898. [ link ] [ pdf ]
Smith J, Calidas D, Schmidt H, Lu T, Rasoloson D, Seydoux G. (2016) Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3. eLife 2016;10.7554/eLife.21337. [ link ]
Wang, Y., Chang, H., Rattner, A., and Nathans, J. (2016) Frizzled receptors in development and disease. Current Topics in Developmental Biology 117: 113-139. [ pdf ]
Wang, Y., Williams, J., Rattner, A., Wu, S., Bassuk, A.G., Goffinet, A.M., and Nathans, J. (2016) Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling.  Developmental Biology 419: 298-310. [ pdf ]
Wang F, Ranjan A, Wei D, Wu C. (2016) Comment on "A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme". Science 353(6297):358, PMID: 27463665. [ pdf ]
Lambrus, B.G., Daggubati, V., Uetake, Y., Scott, P.M., Clutario, K.M., Sluder, G., Holland, A.J. (2016) A USP28-53BP1-p53-p21 signaling axis arrests growth following centrosome loss or prolonged mitosis. Journal of Cell Biology 214:143-153. [ link ] [ pdf ]
Greider, C.W. (2016) Regulating telomere length from the inside out: the replication fork model. Genes & Development 30(13):1483-1491.   [ pdf ]
Nathans, J. and Sterling, P. (2016) How scientists can reduce their carbon footprint. eLife 5: e15928. [ pdf ]
Liang X, Shan S, Pan L, Zhao J, Ranjan A, Wang F, Zhang Z, Huang Y, Feng H, Wei D, Huang L, Liu X, Zhong Q, Lou J, Li G, Wu C, Zhou, Z. (2016) Structural basis of H2A.Z recognition by SRCAP chromatin remodelling subunit YL1. Nat Struct Mol Biol. 23(4):317-23. Epub Mar 14. [ pdf ]
Mo, A., Luo, C., Davis, F.P., Mukamel, E.A., Henry, G.L., Nery, J.R., Urich, M.A., Picard, S., Lister, R., Eddy, S.R., Beer, M.A., Ecker, J.R., and Nathans, J. (2016) Epigenomic landscapes of retinal rods and cones. eLife 5: e11613. [ pdf ]
Liu B, Zheng Y, Yin F, Yu J, Silverman N, Pan D. (2016) Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila. Cell, 36: 246-248.   [ pdf ]
Desiderio S. (2016) Pumping the breaks on B cell development. J Exp Med. 2016 Feb 8;213(2):140.  [ link ]
Hong J, Feng H, Wang F, Ranjan A, Chen J, Jiang J, Ghirlando R, Xiao TS, Wu C, Bai Y. (2014) The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer. Mol Cell. 53:498-505. [ pdf ]
Cho S, Dickey SW, Urban S. (2016) Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Molecular Cell 61(3):329-40. [ link ] [ pdf ]
Niederer, R.O., Papadopoulos, N., and Zappulla, D.C. (2016) Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq. Scientific Reports 6, 19376; doi: https://doi.org/10.1038/srep19376 [ link ]
Abrahamsson S, Ilic R, Wisniewski J, Mehl B, Yu L, Chen L, Davanco M, Oudjedi L, Fiche J, Hajj B, Jin X, Pulupa J, Cho C, Mir M, El Beheiry M, Darzacq X, Nollmann M, Dahan M, Wu C, Lionnet T, Liddle A, Bargmann C. (2016) Multifocus microscopy with precise color multi-phase diffractive optics applied in functional neuronal imaging. Biomedical Optics Express 7(3):855-869. [ pdf ]

2015

Lee, S, S., Bohrson, C. Pike, A.M., Whellan, S.J., and Greider, C.W. (2015) ATM kinase is required for telomere elongation in mouse and human cells. Cell Reports 13(8):1623-1632. [ pdf ]
Chang, H., Smallwood, P.M., Williams, J., and Nathans, J. (2016) The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation. Developmental Biology 409: 181-193. [ pdf ]
Paix A, Folkmann A, Rasoloson D, Seydoux G. (2015) High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes. Genetics 201(1):47-54. [ pdf ]
Sun GJ, Zhou Y, Stadel RP, Moss J, Yong JH, Ito S, Kawasaki NK, Phan AT, Oh JH, Modak N, Reed RR, Toni N, Song H, Ming GL. (2015) Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain. Proceedings of the National Academy of Sciences USA 112(30):9484-9. [ pdf ]
Buhr ED, Yue WW, Ren X, Jiang Z, Liao HW, Mei X, Vemaraju S, Nguyen MT, Reed RR, Lang RA, Yau KW, Van Gelder RN. Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. (2015) Proceedings of the National Academy of Sciences USA. 112(42):13093-8.  [ pdf ]
DiGirolamo DJ, Singhal V, Chang X, Lee SJ, Germain-Lee EL. (2015) Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfecta. Bone Research Feb 10;3:14042. [ pdf ]
Lee YS, Lehar A, Sebald S, Liu M, Swaggart KA, Talbot CC Jr, Pytel P, Barton ER, McNally EM, Lee SJ. (2015) Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy. Human Molecular Genetics 24:(20):5711-9.  [ pdf ]
Zheng Y, Wang W, Liu B, Deng H, Uster E, and Pan D. (2015) Identification of Happyhour/MAP4K as alternative Hpo/Mst-like kinases in the Hippo kinase cascade. Developmental Cell, 34: 642-655. [ link ] [ pdf ]
Cai, J., Maitra, A., Anders, R.A., Taketo, M.M., and Pan, D. (2015) beta-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis. Genes & Devopment., 29: 1493-1506. [ pdf ]
Chen Q, Zhang, N., Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, and Pan D. (2015) Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP. Genes & Development., 29: 1285-1297. [ pdf ]
Deng H, Wang W, Yu J, Zheng Y, Qing Y, and Pan D. (2015) Spectrin regulates Hippo signaling by modulating cortical actomyosin activity. eLife, Mar 31:e06567. doi: 10.7554/eLife.06567.  [ pdf ]
Mefford, M.A. and Zappulla, D.C. (2016) Physical connectivity mapping by circular permutation of human telomerase RNA reveals new regions critical for activity and processivity. Molecular and Cellular Biology 36:251–261. [ link ]
Kaizer H, Connelly CJ, Bettridge K, Viggiani C, Greider CW. (2015) Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 in Saccharomyces cerevisiae. Genetics 201:573-586. [ pdf ]
Koutmou KS, Schuller AP, Brunelle JL, Radhakrishnan A, Djuranovic S, Green R. (2015) Ribosomes slide on lysine-encoding homopolymeric A stretches. Elife 4 doi: 10.7554/eLife.05534. [ pdf ]
Woolstenhulme CJ, Guydosh NR, Green R, Buskirk AR. (2015) High-precision analysis of translational pausing by ribosome profiling in bacteria lacking EFP. Cell Reports 11(1):13-21. [ pdf ]
Kowalinski E, Schuller A, Green R, Conti E. (2015) Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases. Structure 23(7):1336-43. [ pdf ]
Young DJ, Guydosh NR, Zhang F, Hinnebusch AG, Green R. (2015) Rli1/ABCE1 Recycles Terminating Ribosomes and Controls Translation Reinitiation in 3'UTRs In Vivo. Cell 162(4):872-84. [ pdf ]
Arthur L, Pavlovic-Djuranovic S, Smith-Koutmou K, Green R, Szczesny P, Djuranovic S. (2015) Translational control by lysine-encoding A-rich sequences. Science Advances 1(6): soi:10.1126/sciadv. 1500154. [ pdf ]
Lu C, Ward A, Bettridge J, Liu Y, Desiderio S. (2015) An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation. Cell Reports 10(1): 29-38. [ pdf ]
Zordan RE, Beliveau BJ, Trow JA, Craig NL, Cormack BP. (2015) Avoiding the ends: internal epitope tagging of proteins using transposon Tn7. Genetics 200(1):47-58. [ pdf ]
Li CX, Gleason JE, Zhang SX, Bruno VM, Cormack BP, Culotta VC. (2015) Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase. Proceedings of the National Academy of Sciences USA 112:38, E5336-E5342. [ pdf ]
Chang, H., Cahill, H., Smallwood, P.M., Wang, Y., and Nathans, J. (2015) Identification of Astrotactin2 as a genetic modifier that regulates the global orientation of mammalian hair follicles. PLOS Genetics 11: e1005532. [ pdf ]
Hass, E. and Zappulla, D.C. (2015) The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae. eLIFE 2015; 10.7554/eLife.07750  [ link ]
Lambrus BG, Uetake Y, Clutario KM, Daggubati V, Snyder M, Sluder G, Holland AJ. (2015) p53 protects against genome instability following centriole duplication failure. Journal of Cell Biology 210(1), 63-77. [ pdf ]
Baker RP, Urban S. (2015) Cytosolic extensions directly regulate a rhomboid protease by modulating substrate gating. Nature 523, 101–105. [ link ]
Ranjan A, Wang F, Wei D, Huang Y, Wu C. (2015) Nucleosome H2A histone fold and DNA elements activate SWR1-mediated H2A.Z replacement. eLIFE June 27. [ pdf ]

Pages